Five Letters to Charles Prentice, 1925–26

The Life and Letters of Charles Darwin

THE LIFE AND LETTERS OF CHARLES DARWIN. Francis Darwin, Ed., New York, Basic Books, 1959. 2 vols., 1,142 pp. $10.00. The centennial annniversary of the publication of The Origin of Species is being marked with a rash of newly published biographies and commentaries on Charles Darwin. The renewed acclaim is not undeserved, for with the perspective that one hundred years lends, his magnificent syn...

04 Prentice

Obesity plays a central role in the development of the thrifty phenotype. The metabolic disturbances of the cardiovascular metabolic syndrome, frequently ascribed to the thrifty phenotype, are rare in the absence of obesity and their expression is generally proportional to the size of the excess fat mass. Thus obesity interacts with early-life programming in the establishment of disease. Surpri...

Research-agenda Bias: letters to the editor

Metropolitan medicine and the man-midwife: the early life and letters of Charles Locock.

Charles Locock and his times CHARLES later Sir Charles Locock (1799-1875), the son of a Northampton physician, aspired early to his father's profession. His wish, however, was soon to combine this conventional aspiration with the incipient specialist's role that, in bare outline, was taking shape in the 1820s and 1830s.' Buttressing this view of Locock, and spanning more than two decades of his...

Letters to the editors.

Dear Sirs, In their letter Chatauret et al. [1] address an interesting issue: in hypothermic machine perfusion for kidney preservation we should have a better understanding of the machine effects versus solution effects. During the discussions concerning the study design the scientific steering committee also discussed which preservation solutions should be used. For more than 40 years, KPS-1 i...